iSOCO: Intelligent Software Components S.A., Spain

Intelligent Software Components (iSOCO), S.A. is a private company founded in 1999 as a spin-off of the Spanish Scientific Research Council (CSIC/IIIA) in Barcelona. Currently, iSOCO employs around 80 persons in offices in Barcelona, Madrid, Valencia, and Pamplona. In order to ensure the proper transfer of the research to the market, iSOCOLab was created in January 2001, as the Research department with three main objectives: maintain the technological level of the company, develop new prototypes to approach the market through new products and ensure the application of new technologies to business processes. iSOCO has ample experience in international R&D projects, including EU funded, and is successful in bringing research results to the market. Based on the results of FP5, FP6, and FP7 projects in the area of Semantic Web (IBROW, Esperonto, SWWS, Simweb, DIP, SEKT, HOPS, OntoGrid, NeOn, SUPER, ACTIVE, SOA4ALL, GLOCAL), it has renewed its service offering being the first company in Spain to offer Semantic Web technology solutions.

UNIMAN: University of Manchester, School of Computer Science, Manchester, United Kingdom

The University of Manchester is a leading research and education institute, part of the elite Russell Group of UK universities. It has an international reputation in the application of leading edge computing to the Life Sciences and Clinical Sciences. The Manchester Centre for Interdisciplinary Systems Biology pioneers the development and exploitation of new experimental and computational technologies in Systems Biology. Contributions include the COPASI and JWS Online and the SBRML specification. The School of Computer Science has a world leading research programme in e-Science working in scientific workflow systems, data management and integration, data provenance, grid computing, knowledge management, the semantic web, and ontologies. Manchester has built several well-known biomedical data management systems (e.g. TAMBIS, e-Fungi, COGEME). Manchester has a strong track-record in software delivery and is part of OMII-UK which hardens the software outcomes of the UK e-Science.

UPM: Universidad Politécnica de Madrid, Facultad de Informática, Madrid, Spain

The Universidad Politécnica de Madrid (UPM) is the oldest and largest of the Spanish Technical Universities and covers most Engineering disciplines. UPM has a strong commitment to R&D and Innovation, with more than 200 Research Groups and several Research Institutes and Technological Centres in different knowledge areas. The Ontology Engineering Group (OEG,, led by Prof. Asunción Gómez-Pérez, has been working on the provision of semantic infrastructure since 1995, and is currently composed of researchers from different fields: Ontological Engineering, Data Integration, Semantic Web and Semantic Grid.

OXF: University of Oxford, Department of Zoology, Oxford, UK

The University of Oxford is one of the world's leading academic institutions that is established back the 11th century. The Department of Zoology has a long-standing reputation for world-class research and teaching in a broad spectrum of biological sciences, ranging from ecology and behaviour to molecular evolution, development and infectious disease biology. The Image Bioinformatics Research Group (IBRG) of the Zoology Department is a unique informatics research group that is embedded in a biological research and teaching department. IBRG is also part of the distributed Oxford e-Research Centre, which is an internationally renowned multidisciplinary research unit that works closely together with other research units across the university to enable the use and development of innovative computational and information technology for collaborative research. The current focus of IBRG includes research and development of best practice for the sharing and reuse of biological research data and for semantic enhancement of scientific digital publications that lead to more accessible research data. Our R&D activities include the development of biological research data databases and data management tools to support scientific research, the creation and community development of provenance vocabularies and standards, and the development of data web applications to enable integration of heterogeneous information from distributed sources.

PSNC: Poznan Supercomputing and Networking Center. Poznan, Poland

Poznan Supercomputing and Networking Center (PSNC) was established in 1993 by the State Committee for Scientific Research. PSNC is responsible for the management of the countrywide Polish National Research and Educational Network (NREN) Polish Optical Internet PIONIER, which is an advanced network built on PSNC's own fibres with 10GE technology. From the very beginning PSNC served as an HPC service provider, the operator of Poznan Metropolitan Area Network (POZMAN) and a network services provider.

IAA: Instituto de Astrofísica de Andalucía, Granada, Spain

The IAA is an institute of Consejo Superior de Investigaciones Científicas (CSIC) in Granada - Andalucía. The activities of the IAA (CSIC) are related to research in the field of Astrophysics and the development of instruments for telescopes and space vehicles. The IAA has made it a general scientific objective to help increase the bulk of knowledge about our universe, from the closest at hand, our solar system, to an overall scale of the entire universe, improving descriptions and analysing the physical processes that take place there. The nature of this aim demands a multi-disciplinary approach, requiring a combination of theory, observation and technology in different areas of physics and engineering. Although the IAA is a centre for pursuing basic science, we are aware of the role that astrophysics plays as a user and producer of new technologies.

LUMC: Leiden University Medical Centre, Centre for Human and Clinical Genetics, The Netherlands

The department of Human Genetics is led by Professor Dr. Gertjan van Ommen, who is among the leaders in human genetics worldwide. He is past president of HUGO and the Dutch and European Society of Human Genetics, and is Editor in Chief of the European Journal of Human Genetics and director of the Centre for Medical Systems Biology, a multi-local genomics center of excellence in the field of common and rare disorders. He has played a critical role in numerous international research efforts and has played a key role in the development of the Biobanking research infrastructure in the European Strategy Forum on Research Infrastructures (ESFRI) Roadmap. His leadership has contributed to advancement of genome technology, functional genomics novel diagnostics and bioinformatics of human diseases. The research within the department focuses on 9 major research themes: muscular dystrophy, neurogenetics, medical epigenetics, tumor genetics, vascular genetics, population genetics, immunogenetics, developmental biology and technology platforms and facilities. Two subgroups are particularly relevant for Wf4Ever. The group of Professor Johan Den Dunnen is dedicated to the unraveling of molecular mechanisms underlying skeletal muscle differentiation, neuromuscular disease and Huntington's disease. The group develops and applies state-of-the-art genome technologies, mainly in the fields of transcriptomics and genome variation analysis. The BioSemantics group coordinated by Dr. Barend Mons and Dr. Marco Roos focuses on the application of semantic technologies for biomedical applications. This group has a second branch at the Erasmus Medical Centre in Rotterdam, Department of Medical Informatics. This group focuses on sophisticated knowledge discovery methods based on concept profiles and concept disambiguation. The BioSemantics collaboration is complemented by the Adaptive Information Disclosure group, a collaboration of knowledge workers at the Informatics Institute of the University of Amsterdam (groups of prof. Dr. Pieter Adriaans and prof. Dr. Maarten de Rijke, and embedded bioinformaticians' Dr. Scott Marshall, and Dr. Marco Roos) and the Free University of Amsterdam (groups of prof. Dr. Guus Schreiber, and prof. Dr. Frank van Harmelen). In the context of biomedical applications, this consortium combines expertise in knowledge extraction and knowledge management, literature mining and data integration, Service Oriented Architecture, Workflows, Semantic Web, Web2.0, and e-Science. The consortium collaborates with the Netherlands Bioinformatics Centre (NBIC), the Open Middleware Infrastructure Institute UK (OMII-UK), and participates in the W3C Health Care and Life Science Interest Group and the Concept Web Alliance.

Project ID card

Funded under: FP7 (Seventh Framework Programme)

Area: Digital Libraries and Digital Preservation. (ICT-2009.4.1)

Project reference: 270192

Total cost: 3.86 million euro

EU contribution: 2.94 million euro

Execution: From 2010-12-01 to 2013-11-30

Duration: 36 months

Contract type: Collaborative project (STREP)